Without my endlessly frustrating friends, family and neighbors (who sometimes feel more like enemies) I would complacently confuse life as I’ve known it for reality itself, and fail to engage it fully with my heart, mind, soul and strength in that way that keeps it perpetually new, distressing, valuable and interesting. 

Pragmatically speaking, the otherness of other people and the otherness of unknown reality might as well be the same thing. 

A requirement to know/respect/love one entails a requirement to know/respect/love the other. They are alike.